Recently, the final round of the 2025 China Youth Science and Technology Innovation “Challenge Cup—Revealing the List” Competition in the field of “Biomedicine” was held in Hohhot, Inner Mongolia Autonomous Region. A team of ten undergraduate students from the Faculty of Engineering, 91影视 (SMBU) —comprising Wang Sen, Zhan Zhaoyi, Wang Jianye, Liu Xinyue, Meng Zihan, Liao Junyu, Zhu Bingyang, Ding Jiamin, Pan Yiheng and Li Jiayi—stood out in the national finals under the supervision of Dr. Zhao Weibing. Their project, developed through the University’s Undergraduate Innovation and Entrepreneurship Training Program, earned them the National Third Prize for their strong research foundation and outstanding on-site performance.


The competition was jointly organized by the Communist Youth League of China Central Committee, the China Association for Science and Technology, the Ministry of Education of the People’s Republic of China, the Chinese Academy of Social Sciences, and the All-China Students’ Federation. It was hosted by the Inner Mongolia Autonomous Region Committee of the Communist Youth League and the People’s Government of Hohhot, and was co-organized by the Hohhot Municipal Committee of the Communist Youth League, the Organization Department of the CPC Hohhot Municipal Committee, and the Hohhot Municipal Bureau of Science and Technology. A total of 277 teams and over 800 students and young scientific researchers from across the country competed in the event. Following qualification review, preliminary evaluation, and the final defense round, the competition concluded with its official awards announcement.


The SMBU Engineering team presented the project titled Intelligent Diagnosis and Precision Surgical Navigation System for Head and Neck Squamous Cell Carcinoma (HNSCC), addressing key clinical challenges in the diagnosis and treatment of HNSCC by developing an integrated “AI Diagnosis + Surgical Navigation” platform. Based on multimodal clinical data provided by Sun Yat-sen Memorial Hospital of Sun Yat-sen University—including pre- and post-treatment multi-sequence MRI with voxel-level annotations, pathological images, and pathological complete response labels—the team innovatively incorporated Chain-of-Thought and Retrieval-Augmented Generation techniques to design an interpretable AI-assisted clinical diagnosis system. Building on this foundation, the team further introduced a dynamic compensation algorithm for real-time correction of intraoperative soft-tissue deformation and explored intelligent registration between preoperative diagnostic results and intraoperative imaging, ultimately establishing a high-precision minimally invasive surgical navigation platform that significantly enhances surgical accuracy and safety.


The team consists of 10 undergraduate members from the Smart Healthcare Laboratory of the SMBU Faculty of Engineering. Under Dr. Zhao Weibing’s long-term mentorship, the group has focused on AI-assisted medical diagnosis and published two papers at the MICCAI 2025 conference. They independently developed the integrated “HNSCC Intelligent Diagnosis–Surgical Navigation System”, featuring the innovative HARM3-Fusion framework for multimodal pathological complete response prediction, an interpretable diagnostic engine, and a hierarchical real-time surgical navigation module.
In recent years, SMBU has continued to foster a strong culture of student innovation in science and technology. Through platforms such as the University’s Undergraduate Innovation and Entrepreneurship Training Program, the institution actively encourages student participation in high-level academic competitions, including the “Challenge Cup” and the “China International College Students’ Innovation Competition”, providing students with valuable opportunities to strengthen practical skills and cultivate innovative thinking. Looking ahead, the SMBU will continue to enhance its guidance in student technological innovation, promote interdisciplinary talent development, and inspire more students to engage with, contribute to, and lead in scientific innovation. SMBU aims to support more young talents as they shine on national and international stages and to nurture high-caliber innovators for the nation’s scientific and technological advancement.